CELL CYCLE AND CELL DIVISION BEST 100 MCQS

100 BEST MCQS ON CELL CYCLE AND CELL DIVISION

CELL CYCLE CELL DIVISION | NALANDA SCHOLARSMCQS BY NALANDA SCHOLARS CELL CYCLE CELL DIVISION

1. Which of the following is not a phase of the cell cycle?
A) G1 phase
B) G2 phase
C) M phase
D) Interphase

2. During which phase of the cell cycle does DNA replication occur?
A) G1 phase
B) G2 phase
C) S phase
D) M phase

3. What is the purpose of cell division?
A) To increase cell size
B) To repair damaged tissues
C) To produce new cells
D) To reduce the number of cells

4. The phase of the cell cycle in which the cell spends most of its time is:
A) G1 phase
B) S phase
C) G2 phase
D) M phase

5. Which checkpoint ensures that DNA replication has been completed before cell division proceeds?
A) G1 checkpoint
B) S checkpoint
C) G2 checkpoint
D) M checkpoint

6. Which of the following is not a stage of mitosis?
A) Prophase
B) Interphase
C) Metaphase
D) Telophase

7. What is cytokinesis?
A) Division of the cytoplasm
B) Division of the nucleus
C) Formation of spindle fibers
D) Duplication of DNA

8. Which of the following is true about meiosis?
A) It produces identical daughter cells
B) It involves two rounds of cell division
C) It occurs only in somatic cells
D) It results in diploid daughter cells

9. Which of the following is not a function of mitosis?
A) Growth
B) Repair
C) Asexual reproduction
D) Production of gametes

10. The process by which a diploid cell becomes four haploid cells is called:
A) Mitosis
B) Meiosis
C) Cytokinesis
D) Interphase

11. Crossing over occurs during which stage of meiosis?
A) Prophase I
B) Metaphase I
C) Anaphase I
D) Telophase I

12. How many chromosomes are present in a human somatic cell after mitosis?
A) 23
B) 46
C) 92
D) 69

13. Which of the following statements is true regarding cancer cells?
A) They undergo programmed cell death.
B) They exhibit uncontrolled cell division.
C) They respond normally to growth factors.
D) They have functional tumor suppressor genes.

14. Cyclins and cyclin-dependent kinases (CDKs) play a crucial role in regulating:
A) DNA replication
B) Mitosis
C) Meiosis
D) Cytokinesis

15. Which phase of the cell cycle follows cytokinesis?
A) G1 phase
B) S phase
C) G2 phase
D) Interphase

16. The spindle fibers attach to chromosomes at the:
A) Centromere
B) Telomere
C) Kinetochore
D) Centriole

17. The cell plate is formed during cytokinesis in:
A) Animal cells
B) Plant cells
C) Both animal and plant cells
D) Neither animal nor plant cells

18. In which phase of mitosis do sister chromatids separate and move to opposite poles of the cell?
A) Prophase
B) Metaphase
C) Anaphase
D) Telophase

19. Which of the following is a characteristic of anaphase in mitosis?
A) Chromosomes condense
B) Nuclear envelope breaks down
C) Chromatids line up at the equatorial plate
D) Spindle fibers begin to disassemble

20. Which checkpoint ensures that the cell has enough energy and resources to undergo division?
A) G1 checkpoint
B) S checkpoint
C) G2 checkpoint
D) M checkpoint

21. What is the end result of meiosis II?
A) Four haploid daughter cells
B) Two diploid daughter cells
C) One diploid and one haploid daughter cell
D) Two haploid daughter cells

22. Which of the following is not a phase of interphase?
A) G1 phase
B) S phase
C) M phase
D) G2 phase

23. In which stage of mitosis do the chromosomes align along the equatorial plane of the cell?
A) Prophase
B) Metaphase
C) Anaphase
D) Telophase

24. Which of the following is not a characteristic of cancer cells?
A) Contact inhibition
B) Loss of cell cycle control
C) Ability to metastasize
D) Unlimited replicative potential

25. Which enzyme is responsible for catalyzing the addition of phosphate groups to cyclins, activating them?
A) Cyclin-dependent kinase (CDK)
B) Cyclin-dependent kinase inhibitor (CKI)
C) Cyclin-dependent kinase activator (CKA)
D) Cyclin-dependent kinase phosphatase (CKP)

26. During which phase of the cell cycle does the cell grow and prepare for DNA replication?
A) G1 phase
B) S phase
C) G2 phase
D) M phase

27. The process of nuclear division in eukaryotic cells is called:
A) Cytokinesis
B) Meiosis
C) Mitosis
D) Binary fission

28. Which of the following is not a function of the centrioles during cell division?
A) Formation of spindle fibers
B) Organization of microtubules
C) Synthesis of DNA
D) Anchoring of spindle fibers

29. The G1 checkpoint ensures that:
A) Chromosomes are properly aligned
B) DNA has been replicated correctly
C) Cell size is adequate for division
D) Sister chromatids separate correctly

30. During which phase of meiosis do homologous chromosomes separate?
A) Prophase I
B) Metaphase I
C) Anaphase I
D) Telophase I

31. Which of the following accurately describes a haploid cell?
A) Contains two sets of chromosomes
B) Contains one set of chromosomes
C) Contains no chromosomes
D) Contains multiple sets of chromosomes

32. Which of the following is not a characteristic of prophase in mitosis?
A) Chromosomes condense
B) Nuclear envelope breaks down
C) Nucleolus disappears
D) Sister chromatids separate

33. Which phase of mitosis follows metaphase?
A) Prophase
B) Anaphase
C) Telophase
D) Interphase

34. Which of the

following events occurs during telophase?
A) Chromosomes condense
B) Nuclear envelope forms around chromosomes
C) Sister chromatids separate
D) Spindle fibers begin to disassemble

35. Which of the following is true regarding gametes?
A) They are diploid cells
B) They are produced by mitosis
C) They undergo meiosis to form haploid cells
D) They are produced by somatic cells

36. Which phase of the cell cycle is characterized by rapid cell growth and protein synthesis?
A) G1 phase
B) S phase
C) G2 phase
D) M phase

37. The process of DNA replication occurs during which phase of the cell cycle?
A) G1 phase
B) S phase
C) G2 phase
D) M phase

38. Which of the following is true regarding homologous chromosomes?
A) They carry identical genetic information
B) They separate during anaphase II of meiosis
C) They pair up during prophase I of meiosis
D) They are produced during mitosis

39. Which of the following statements is true regarding the G2 phase checkpoint?
A) It ensures that DNA replication has been completed
B) It checks for cell size and nutrient availability
C) It ensures proper alignment of chromosomes
D) It monitors spindle fiber attachment to kinetochores

40. Which phase of the cell cycle immediately precedes cytokinesis?
A) G1 phase
B) S phase
C) G2 phase
D) M phase

41. Which of the following is a characteristic of anaphase II in meiosis?
A) Homologous chromosomes separate
B) Sister chromatids separate
C) Chromosomes align along the equatorial plane
D) Spindle fibers begin to disassemble

42. Which of the following accurately describes a diploid cell?
A) Contains two sets of chromosomes
B) Contains one set of chromosomes
C) Contains no chromosomes
D) Contains multiple sets of chromosomes

43. The process of cytokinesis in animal cells involves the formation of a:
A) Cell plate
B) Cleavage furrow
C) Cell wall
D) Contractile ring

44. Which of the following statements is true regarding the cell cycle?
A) The duration of each phase is fixed and unchangeable
B) Cells spend the most time in M phase
C) Interphase is the only phase where DNA replication occurs
D) Cells can exit the cell cycle and enter a non-dividing state

45. The process of DNA condensation, where chromatin fibers coil and condense into visible chromosomes, occurs during:
A) Interphase
B) Prophase
C) Metaphase
D) Telophase

46. Which of the following is not a characteristic of telophase in mitosis?
A) Chromosomes decondense
B) Nuclear envelope reforms
C) Spindle fibers disassemble
D) Sister chromatids separate

47. The process of crossing over occurs between:
A) Sister chromatids
B) Homologous chromosomes
C) Non-homologous chromosomes
D) Centromeres

48. Which of the following statements is true regarding the G1 checkpoint?
A) It ensures that DNA replication has been completed
B) It monitors spindle fiber attachment to kinetochores
C) It checks for cell size and nutrient availability
D) It ensures proper alignment of chromosomes

49. The main difference between mitosis and meiosis is:
A) The number of daughter cells produced
B) The presence of cytokinesis
C) The number of DNA replication cycles
D) The presence of homologous chromosomes pairing

50. Which of the following is not a stage of interphase?
A) G0 phase
B) G1 phase
C) S phase
D) G2 phase

51. The process of chromosome alignment along the equatorial plane of the cell occurs during:
A) Prophase
B) Metaphase
C) Anaphase
D) Telophase

52. The phase of the cell cycle during which the cell prepares for mitosis by condensing its chromosomes and organizing its cytoskeleton is:
A) G1 phase
B) S phase
C) G2 phase
D) M phase

53. Which of the following is true regarding the G2 checkpoint?
A) It ensures that DNA replication has been completed
B) It checks for cell size and nutrient availability
C) It ensures proper alignment of chromosomes
D) It monitors spindle fiber attachment to kinetochores

54. The spindle fibers are composed of:
A) Actin filaments
B) Intermediate filaments
C) Microtubules
D) Myosin filaments

55. Which of the following is not a function of mitosis?
A) Growth
B) Repair
C) Genetic diversity
D) Asexual reproduction

56. The process by which a cell divides into two daughter cells with identical genetic information is called:
A) Mitosis
B) Meiosis
C) Cytokinesis
D) Interphase

57. Which of the following is true regarding the G1 phase of the cell cycle?
A) It is the longest phase of the cell cycle
B) It is the phase during which DNA replication occurs
C) It is the phase during which the cell prepares for mitosis
D) It is the phase during which the cell prepares for cytokinesis

58. Which of the following statements is true regarding the centromere?
A) It is the region of the chromosome where DNA replication occurs
B) It is the site where spindle fibers attach to the chromosome
C) It is the region of the chromosome where sister chromatids separate
D) It is the site of RNA synthesis during mitosis

59. Which of the following is not a function of spindle fibers during cell division?
A) Organization of microtubules
B) Formation of the mitotic spindle
C) Separation of sister chromatids
D) Duplication of DNA

60. The process of cell division in prokaryotic cells is called:
A) Mitosis
B) Meiosis
C) Cytokinesis
D) Binary fission

61. Which of the following is not a characteristic of anaphase II in meiosis?
A) Homologous chromosomes separate
B) Sister chromatids separate
C) Chromosomes align along the equatorial plane
D) Spindle fibers begin to disassemble

62. The division of the cytoplasm following nuclear division is called:
A) Mitosis
B) Meiosis
C) Cytokinesis
D) Interphase

63. Which of the following accurately describes a haploid cell?
A) Contains two sets of chromosomes
B) Contains one set of chromosomes

C) Contains no chromosomes
D) Contains multiple sets of chromosomes

64. The structure that organizes the microtubules during cell division is called the:
A) Centromere
B) Centriole
C) Kinetochore
D) Cleavage furrow

65. Which of the following is a characteristic of anaphase in mitosis?
A) Chromosomes condense
B) Nuclear envelope breaks down
C) Chromatids line up at the equatorial plate
D) Spindle fibers begin to disassemble

66. The process of DNA replication occurs during which phase of the cell cycle?
A) G1 phase
B) S phase
C) G2 phase
D) M phase

67. The spindle fibers attach to chromosomes at the:
A) Centromere
B) Telomere
C) Kinetochore
D) Centriole

68. Which of the following accurately describes a diploid cell?
A) Contains two sets of chromosomes
B) Contains one set of chromosomes
C) Contains no chromosomes
D) Contains multiple sets of chromosomes

69. Which of the following is not a characteristic of prophase in mitosis?
A) Chromosomes condense
B) Nuclear envelope breaks down
C) Nucleolus disappears
D) Sister chromatids separate

70. Which phase of mitosis follows metaphase?
A) Prophase
B) Anaphase
C) Telophase
D) Interphase

71. Which of the following events occurs during telophase?
A) Chromosomes condense
B) Nuclear envelope forms around chromosomes
C) Sister chromatids separate
D) Spindle fibers begin to disassemble

72. Which of the following is true regarding gametes?
A) They are diploid cells
B) They are produced by mitosis
C) They undergo meiosis to form haploid cells
D) They are produced by somatic cells

73. The process of nuclear division in eukaryotic cells is called:
A) Cytokinesis
B) Meiosis
C) Mitosis
D) Binary fission

74. Which of the following is true regarding homologous chromosomes?
A) They carry identical genetic information
B) They separate during anaphase II of meiosis
C) They pair up during prophase I of meiosis
D) They are produced during mitosis

75. Which of the following statements is true regarding the G1 checkpoint?
A) It ensures that DNA replication has been completed
B) It monitors spindle fiber attachment to kinetochores
C) It checks for cell size and nutrient availability
D) It ensures proper alignment of chromosomes

76. The main difference between mitosis and meiosis is:
A) The number of daughter cells produced
B) The presence of cytokinesis
C) The number of DNA replication cycles
D) The presence of homologous chromosomes pairing

77. The process of DNA condensation, where chromatin fibers coil and condense into visible chromosomes, occurs during:
A) Interphase
B) Prophase
C) Metaphase
D) Telophase

78. Which of the following is not a characteristic of telophase in mitosis?
A) Chromosomes decondense
B) Nuclear envelope reforms
C) Spindle fibers disassemble
D) Sister chromatids separate

79. The process of crossing over occurs between:
A) Sister chromatids
B) Homologous chromosomes
C) Non-homologous chromosomes
D) Centromeres

80. Which of the following statements is true regarding the G1 phase of the cell cycle?
A) It is the longest phase of the cell cycle
B) It is the phase during which DNA replication occurs
C) It is the phase during which the cell prepares for mitosis
D) It is the phase during which the cell prepares for cytokinesis

81. Which of the following statements is true regarding the centromere?
A) It is the region of the chromosome where DNA replication occurs
B) It is the site where spindle fibers attach to the chromosome
C) It is the region of the chromosome where sister chromatids separate
D) It is the site of RNA synthesis during mitosis

82. Which of the following is not a function of spindle fibers during cell division?
A) Organization of microtubules
B) Formation of the mitotic spindle
C) Separation of sister chromatids
D) Duplication of DNA

83. The division of the cytoplasm following nuclear division is called:
A) Mitosis
B) Meiosis
C) Cytokinesis
D) Interphase

84. Which of the following accurately describes a haploid cell?
A) Contains two sets of chromosomes
B) Contains one set of chromosomes
C) Contains no chromosomes
D) Contains multiple sets of chromosomes

85. The structure that organizes the microtubules during cell division is called the:
A) Centromere
B) Centriole
C) Kinetochore
D) Cleavage furrow

86. Which of the following is a characteristic of anaphase in mitosis?
A) Chromosomes condense
B) Nuclear envelope breaks down
C) Chromatids line up at the equatorial plate
D) Spindle fibers begin to disassemble

87. The process of DNA replication occurs during which phase of the cell cycle?
A) G1 phase
B) S phase
C) G2 phase
D) M phase

88. The spindle fibers attach to chromosomes at the:
A) Centromere
B) Telomere
C) Kinetochore
D) Centriole

89. Which of the following accurately describes a diploid cell?
A) Contains two sets of chromosomes
B) Contains one set of chromosomes
C) Contains no chromosomes
D) Contains multiple sets of chromosomes

90. Which of the following is not a characteristic of prophase in mitosis?
A) Chromosomes condense
B) Nuclear envelope breaks down
C) Nucleolus disappears
D) Sister chromatids separate

91. Which phase of mitosis follows metaphase?
A) Prophase
B) Anaphase
C) Telophase
D) Interphase

92. Which of the following events occurs during telophase?
A) Chromosomes condense
B) Nuclear envelope forms around chromosomes
C) Sister chromatids separate
D) Spindle fibers begin to disassemble

93. Which of the following is true regarding gametes?
A) They are diploid cells
B) They are produced by mitosis
C) They undergo meiosis to form haploid cells
D) They are produced by somatic cells

94. The process of nuclear

division in eukaryotic cells is called:
A) Cytokinesis
B) Meiosis
C) Mitosis
D) Binary fission

95. Which of the following is true regarding homologous chromosomes?
A) They carry identical genetic information
B) They separate during anaphase II of meiosis
C) They pair up during prophase I of meiosis
D) They are produced during mitosis

96. Which of the following statements is true regarding the G1 checkpoint?
A) It ensures that DNA replication has been completed
B) It monitors spindle fiber attachment to kinetochores
C) It checks for cell size and nutrient availability
D) It ensures proper alignment of chromosomes

97. The main difference between mitosis and meiosis is:
A) The number of daughter cells produced
B) The presence of cytokinesis
C) The number of DNA replication cycles
D) The presence of homologous chromosomes pairing

98. The process of DNA condensation, where chromatin fibers coil and condense into visible chromosomes, occurs during:
A) Interphase
B) Prophase
C) Metaphase
D) Telophase

99. Which of the following is not a characteristic of telophase in mitosis?
A) Chromosomes decondense
B) Nuclear envelope reforms
C) Spindle fibers disassemble
D) Sister chromatids separate

100. The process of crossing over occurs between:
A) Sister chromatids
B) Homologous chromosomes
C) Non-homologous chromosomes
D) Centromeres

ANSWER KEY:-

1. D) Interphase
2. C) S phase
3. C) To produce new cells
4. D) Interphase
5. B) S checkpoint
6. B) Interphase
7. A) Division of the cytoplasm
8. B) It involves two rounds of cell division
9. D) Production of gametes
10. B) Meiosis
11. A) Prophase I
12. B) 46
13. B) They exhibit uncontrolled cell division.
14. B) Mitosis
15. D) Interphase
16. C) Kinetochore
17. B) Plant cells
18. C) Anaphase
19. C) Chromatids line up at the equatorial plate
20. A) G1 checkpoint
21. A) Four haploid daughter cells
22. C) M phase
23. B) Metaphase
24. A) Contact inhibition
25. A) Cyclin-dependent kinase (CDK)
26. A) G1 phase
27. D) Binary fission
28. D) Anchoring of spindle fibers
29. C) Cell size is adequate for division
30. D) Telophase I
31. B) Contains one set of chromosomes
32. D) Sister chromatids separate
33. B) Anaphase
34. B) Nuclear envelope forms around chromosomes
35. C) They undergo meiosis to form haploid cells
36. A) G1 phase
37. B) S phase
38. C) They pair up during prophase I of meiosis
39. B) It checks for cell size and nutrient availability
40. C) G2 phase
41. B) Sister chromatids separate
42. A) Contains two sets of chromosomes
43. B) Cleavage furrow
44. D) Cells can exit the cell cycle and enter a non-dividing state
45. B) Prophase
46. D) Sister chromatids separate
47. B) Homologous chromosomes
48. C) It checks for cell size and nutrient availability
49. A) The number of daughter cells produced
50. A) G0 phase
51. B) Metaphase
52. C) It ensures proper alignment of chromosomes
53. D) It monitors spindle fiber attachment to kinetochores
54. C) Microtubules
55. C) Genetic diversity
56. A) Mitosis
57. C) It is the phase during which the cell prepares for mitosis
58. C) It is the region of the chromosome where sister chromatids separate
59. D) Duplication of DNA
60. D) Binary fission
61. C) Chromosomes align along the equatorial plane
62. C) Cytokinesis
63. B) Contains one set of chromosomes
64. B) Centriole
65. B) Nuclear envelope breaks down
66. B) S phase
67. C) Kinetochore
68. A) Contains two sets of chromosomes
69. D) Sister chromatids separate
70. B) Anaphase
71. B) Nuclear envelope forms around chromosomes
72. C) They undergo meiosis to form haploid cells
73. C) Mitosis
74. C) They pair up during prophase I of meiosis
75. C) It checks for cell size and nutrient availability
76. A) The number of daughter cells produced
77. B) Prophase
78. C) Spindle fibers disassemble
79. B) Homologous chromosomes
80. C) It is the phase during which the cell prepares for mitosis
81. C) It is the region of the chromosome where sister chromatids separate
82. D) Duplication of DNA
83. C) Cytokinesis
84. B) Contains one set of chromosomes
85. B) Centriole
86. B) Nuclear envelope breaks down
87. B) S phase
88. C) Kinetochore
89. A) Contains two sets of chromosomes
90. D) Sister chromatids separate
91. C) Telophase
92. B) Nuclear envelope forms around chromosomes
93. C) They undergo meiosis to form haploid cells
94. C) Mitosis
95. C) They pair up during prophase I of meiosis
96. C) It checks for cell size and nutrient availability
97. A) The number of daughter cells produced
98. B) Prophase
99. C) Spindle fibers disassemble
100. B) Homologous chromosomes

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